Combination Bupropion / Varenicline for Smoking Cessation in Male Smokers 

Screening-Button               

 

This study is available in Charlotte, RDU, and Winston-Salem

The purpose of this study is to evaluate whether the use of Chantix and Zyban together or Chantix alone is more successful to help men quit smoking.

This study consists of a physical screening session (scheduled between 8:00 am and 2:30 pm Monday through Friday) and seven study visits over a 13-week period. You may also be asked to come in for a follow-up visit six months after your quit day. Your entire participation, including six-month follow-up, will last approximately seven months.

The physical screening visit will take approximately 2 to 2 ½ hours, and includes a physical exam and a drug screening test. If you test positive for illegal drugs, you will not be eligible to participate.

 

If the physical screen confirms you are a good match for this study, you will schedule an appointment for your first study visit approximately one week later. Study participants will start out wearing nicotine patches and will be randomly assigned to one of the two study groups (Chantix and Zyban together or Chantix alone). During all study visits we will be measuring the carbon monoxide in your breath, collecting a saliva sample and taking your heart rate, blood pressure, and weight. At each visit you will be asked to fill out questionnaires. Enough study medication will be given to you to last until your next study visit.

 

The first study session will last approximately 1 to 1½ hours, and all other study visits will last approximately 45 minutes to 1 hour. All of the seven study visits will take place between 12 pm and 4 pm Monday through Friday. If you complete all study visits and requirements, you will be compensated up to $350. Study participants will not be compensated for the physical screening visit. You will receive a check in the mail after you complete study participation. Please allow four to six weeks for your payment to be processed. Participants who qualify for and come back for a follow-up study visit six months after their quit day, will receive an additional $60 check in the mail.